Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Toluenesulfonyl chloride → 16-(p-Toluensulfonyloxy)hexadecanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 반응물 | 1,16-Hexadecanediol | HCID 82184 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 16-(p-Toluensulfonyloxy)hexadecanol | HCID 18366472 | — |
반응 단계
To a solution of 1.1 g of 1,16-dihydroxyhexadecane in 10 ml of dry pyridine 0.8 g of tosyl chloride was added. After 2 h mixture was concentrated diluted with 20 ml of acetone, 5 g of SiO2 was added and acetone was removed in vacuum. The solid was applied on SiO2 and eluted with pentane-ethyl acetate (2:1) to yield 748 mg (42%) of C-101.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06130037 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-e13d3a98014543ba8b953bfdfb674d24 |
| 출처 메모 | uspto-grants-2000_10 |