Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Amino-1-(diphenylmethyl)azetidine → 1-(1-Benzhydryl-azetidin-3-ylamino)-3-(2-methyl-benzothiazol-7-yloxy)-propan-2-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Amino-1-(diphenylmethyl)azetidine | HCID 5744546 | — |
| 반응물 | 2-Methyl-7-(oxiranyl-2-ylmethoxy)benzothiazole | HCID 131722120 | — |
| 용매 | Dioxan ethanol | HCID 22560076 | — |
| 생성물 | 1-(1-Benzhydryl-azetidin-3-ylamino)-3-(2-methyl-benzothiazol-7-yloxy)-propan-2-ol | HCID 54077942 | — |
반응 단계
The title compound was prepared according to Method A from 2-methyl-7-(oxiranyl-2-ylmethoxy)benzothiazole and 3-amino-1-benzhydrylazetidine with dioxane/ethanol (1:1) as the solvent. mp 55° C.; LSIMS m/z 460. The 3-amino-1-benzhydrylazetidine was prepared as described in Preparation 96.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06130217 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-09b7a2c5efbc48d7901f72b7881882cf |
| 출처 메모 | uspto-grants-2000_10 |