Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus pentachloride → Pyridine-3-sulfonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus pentachloride | HCID 24819 | — |
| 반응물 | 3-Pyridinesulfonic acid | HCID 69468 | — |
| 용매 | Benzene | HCID 241 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Pyridine-3-sulfonyl chloride | HCID 3164136 | 92% |
반응 단계
3-Pyridylsulfonic acid (30 g, 0.188 mole) was added to PCl5 (46.8 g, 0.225 mole), suspended in 150 mL toluene and heated to reflux overnight. The suspension was cooled and concentrated to yield a yellow oil, which was diluted with benzene, filtered through a pad of celite and concentrated to give 30.7 g (92%) of 23-10 as a yellow oil, which was used in the next step without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05416099 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-bf556213779245328caa8e5257c096ab |
| 출처 메모 | uspto-grants-1995_05 |