4-Chloro-2-phenyl-pyrimidine-5-carboxylic acid benzylamide → HCID 178418303, 화합물

HRID 367230

반응식

HRID 367230 반응식
[CH2:1]([NH:8][C:9]([C:11]1[C:12](Cl)=[N:13][C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:15][CH:16]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[SH2:24].[Na]>>[CH2:1]([NH:8][C:9]([C:11]1[C:12]([SH:24])=[N:13][C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:15][CH:16]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 539375004-Chloro-2-phenyl-pyrimidine-5-carboxylic acid benzylamideHCID 86586439Sodium hydrogen sulphide

생성물 1

HCID 178418303HCID 178418303, 화합물수율 65.2%

실험 절차

Using the procedure from Preparation 34, 5.8 g (17.9 mmol) of 4-chloro-2-phenyl-pyrimidine-5-carboxylic acid benzylamide was reacted with 5.1 g (72 mmol) of sodium hydrogen sulfide to give 3.75 g of the title compound, mp 189-193° C.

출처 및 근거

ORD 기록
ord-9ec569656237450bab672f6d9aff6f93
출처 데이터셋
uspto-grants-2000_10
특허 번호
US06133270

연결된 노트

불러오는 중…