Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetophenone → Ccris 2231
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetophenone | HCID 7410 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-Methoxybenzaldehyde | HCID 31244 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Ccris 2231 | HCID 92853 | 56% |
반응 단계
Step A Add 10% aqueous NaOH (38 mL) to a solution of p-anisaldehyde (25 mL, 0.206 mol) and acetophenone (23.97 mL, 0.206 mol) in EtOH (500 mL). Stir the mixture at room temperature over night. Dilute the mixture with water and extract with ether. Combine the ethereal extracts, wash with water and brine, dry over Na2SO4 and concentrate to a solid. Recrystallize the solid from ether/hexanes to provide 27.51 g (56%) of 4'-methoxychalcone, mp 72°-74° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05416118 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-8a78853258fc48d2bcf415d810e7317d |
| 출처 메모 | uspto-grants-1995_05 |