4-Chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine → 2-(Pyridin-3-yl)-4-(3,4-dichlorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine
반응식
F[C:2]1([Cl:11])[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]1[Cl:10].Cl[C:13]1[C:14]2[C:27]([CH3:28])=[CH:26][S:25][C:15]=2[N:16]=[C:17]([C:19]2[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=2)[N:18]=1>>[N:21]1[CH:22]=[CH:23][CH:24]=[C:19]([C:17]2[N:18]=[C:13]([NH:7][CH2:6][C:5]3[CH:8]=[CH:9][C:2]([Cl:11])=[C:3]([Cl:10])[CH:4]=3)[C:14]3[C:27]([CH3:28])=[CH:26][S:25][C:15]=3[N:16]=2)[CH:20]=1참가 물질
3
실험 절차
With the procedure of Example 1, the reaction of 4-fluoro-3,4-dichlorobenzylamine with 4-chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-3-yl)-4-(3,4-dichlorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine.
출처 및 근거
- ORD 기록
- ord-ede672bcecde48deab8f7c56192f7ac0
- 출처 데이터셋
- uspto-grants-2000_10