Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethoxyethylamine → N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethoxyethylamine | HCID 66970 | — |
| 반응물 | 2-Chloro-6-(trimethylsilyl)benzoyl chloride | HCID 15183557 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide | HCID 18630026 | 66.2% |
반응 단계
The compound of Example b (4.94 g, 20 mmol), 2-ethoxyethyl amine (3.92 g, 44 mmol), and toluene (35 mL) were combined according to General Method E1. The crude product was recrystallized from aq ethanol to afford 3.97 g of N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide as white solid, a 66% yield. m.p. 71-73° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06133252 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-7c7469ef38f34e528b1eecd2407de8d7 |
| 출처 메모 | uspto-grants-2000_10 |