Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Uridine → 2'-O-Nonyluridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Uridine | HCID 6029 | — |
| 반응물 | 1-Iodononane | HCID 20275 | — |
| 반응물 | Dibutyltin oxide | HCID 61221 | — |
| 반응물 | 2',3'-O-dibutylstannyleneuridine | HCID 131720090 | — |
| 생성물 | 2'-O-Nonyluridine | HCID 22874743 | — |
반응 단계
As per the procedure of Example 49, uridine (22.5 g) was treated with dibutyl tin oxide (22.5 g, 1 eq). The resulting 2',3'-O-dibutylstannyleneuridine was treated with iodononane (11 ml, 1.3 eq.) at 130-140° C. as per Example 50 to give the 2' and 3' isomers (11.2 g) as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06133438 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-70c2c22e48174b57af0222159c25dc72 |
| 출처 메모 | uspto-grants-2000_10 |