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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 368816생성일: 2026년 10월 26일

Dichloromethane methanol → 1-[2-(Isochroman-1-yl)ethyl]-4-(3-methoxyphenyl)piperazine dihydrochloride

https://huagongshe.com/reaction/368816

반응식

참여 물질

역할이름HCID투입량
반응물Dichloromethane methanolHCID 21226129—
반응물1-[2-(Isochroman-1-yl)ethyl]-4-(2-methoxyphenyl)piperazine dihydrochloride monohydrateHCID 23288951—
생성물1-[2-(Isochroman-1-yl)ethyl]-4-(3-methoxyphenyl)piperazine dihydrochlorideHCID 23288913—

반응 단계

Following the general procedure of EXAMPLE 1 and making non-critical variations but using 1-(3-methoxyphenyl)piperazine dihydrochloride (XI, 0.5173 g, 1.95 mmol) in place of 1-(2-chlorophenyl)piperazine dihydrochloride (XI), the title compound is obtained (chromatography using methanol/dichloromethane, 1/99), mp 189.5-193°; MS (m/z) 352; IR (mineral oil) 2373, 1460, 1512, 1048, 748 and 1291 cm-1.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06133446
출처 데이터셋uspto-grants-2000_10
ORD IDord-7f9604d87a1f4bbe9a08673fae53c277
출처 메모uspto-grants-2000_10