Methanol → 3-Methoxy-3-oxo-2-phenylpropanoic acid

HRID 36899

반응식

HRID 36899 반응식
[C:1]1([CH:7]([C:11]([OH:13])=[O:12])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.B(F)(F)F.[CH3:18]COCC.CO>>[C:1]1([CH:7]([C:11]([OH:13])=[O:12])[C:8]([O:10][CH3:18])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 887MethanolHCID 8000Boron trifluoride etherateHCID 75791Phenylmalonic acid

생성물 1

HCID 28177753-Methoxy-3-oxo-2-phenylpropanoic acid

실험 절차

A mixture of phenylmalonic acid (3.6 g, 0.02 mol), boron trifluoride etherate (2.4 mL, 0.02 mol) and 0.8 mL of anhydrous methanol (0.02 mol) was refluxed and stirred for 24 hours. After cooling to room temperature, the reaction mixture was filtered and 20 mL of water was added.

후처리

  1. temperaturewas refluxed
  2. filtrationthe reaction mixture was filtered
  3. addition20 mL of water was added

출처 및 근거

ORD 기록
ord-f0fbabcef7fb4ef58e6a505379651e32
출처 데이터셋
uspto-grants-1995_05
특허 번호
US05418244

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