Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydrazinylbenzenesulfonamide hydrochloride → 4-[5-(6-methoxybenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydrazinylbenzenesulfonamide hydrochloride | HCID 2794567 | — |
| 반응물 | 4,4,4-Trifluoro-1-(6-methoxybenzothiazol-2-yl)butane-1,3-dione | HCID 15491098 | — |
| 생성물 | 4-[5-(6-methoxybenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide | HCID 15491099 | — |
반응 단계
The procedure of Example 9 was repeated using 4,4,4-trifluoro-1-(6-methoxybenzothiazol-2-yl)butane-1,3-dione and 4-sulfamoylphenylhydrazine hydrochloride as the starting materials to obtain 4-[5-(6-methoxybenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide. NMR(CDCl3) δ: 3.88 (3H, s), 5.03 (2H, bs), 7.11 (1H, dd, J=2.3 Hz, 8.9 Hz), 7.20 (1H, s), 7.31 (2H, d, J=2.3 Hz), 7.68 (2H, d, J=8.6 Hz), 7.83 (1H, d, J=8.9 Hz), 8.01 (2H, d, J=8.6 Hz); mp 236-237° C. (ethyl acetate-isooctane)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06136831 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-ecbce7ed4cf544fd8510da76b509525e |
| 출처 메모 | uspto-grants-2000_10 |