1-(2-Methoxyphenyl)piperazine → Methyl 3-[4-(4-o-methoxyphenylpiperazino)butyl]indole-5-carboxylate
반응식
Br[CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([C:15]([O:17][CH3:18])=[O:16])[CH:13]=2)[NH:8][CH:7]=1.[CH3:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[CH3:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][N:30]([CH2:2][CH2:3][CH2:4][CH2:5][C:6]2[C:14]3[C:9](=[CH:10][CH:11]=[C:12]([C:15]([O:17][CH3:18])=[O:16])[CH:13]=3)[NH:8][CH:7]=2)[CH2:29][CH2:28]1참가 물질
3
실험 절차
By reaction of methyl 3-(4-bromobutyl)indole-5-carboxylate with 1-(o-methoxyphenyl)piperazine "B" analogously to Example 1, methyl 3-[4-(4-o-methoxyphenylpiperazino)butyl]indole-5-carboxylate is obtained; hydrate, hydrochloride, m.p. 195°-196°.
출처 및 근거
- ORD 기록
- ord-d6d39005fa2d48a18b5e64c86310db4f
- 출처 데이터셋
- uspto-grants-1995_05
- 특허 번호
- US05418237