Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenol → Methyl-4-(trans-3-decenyloxy)-benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenol | HCID 996 | — |
| 반응물 | Methyl 4-(octadecyloxy)benzoate | HCID 4189536 | — |
| 반응물 | 3-Decen-1-ol, (3E)- | HCID 5352493 | — |
| 반응물 | Diethyl azodicarboxylate | HCID 5462977 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Methyl-4-(trans-3-decenyloxy)-benzoate | HCID 18521096 | 85% |
반응 단계
Ester 34 (500 mg, 3.29 mmol), 3-decenol 26h (514 mg, 3.29 mmol), TPP (992 mg, 3.78 mmol), DEAD (658 mg, 3.78 mmol), and 33 ml ether were reacted according to the procedure for compound 35a. The crude product was purified via flash chromatography over silica gel with gradual elutions from 95/5-90/10 (v/v, Hex/EtOAc). Evaporation of solvent yielded 810 mg (85%) of colorless liquid which was not quite pure. The product was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06139771 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-6fce36808b4841f78ea78c017314a9bc |
| 출처 메모 | uspto-grants-2000_10 |