Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethylene Glycol Monoethyl Ether → 3-[4-(4-m-Methoxyphenylpiperazino)butyl]indole-5-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethylene Glycol Monoethyl Ether | HCID 8146 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 3-[4-(4-m-Methoxyphenylpiperazino)butyl]-5-cyanoindole | HCID 19936482 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-[4-(4-m-Methoxyphenylpiperazino)butyl]indole-5-carboxamide | HCID 19936456 | — |
반응 단계
A mixture of 30.6 g of 3-[4-(4-m-methoxyphenylpiperazino)butyl]-5-cyanoindole, 27.1 g of NaOH, 520 ml of water and 420 ml of diethylene glycol monoethyl ether is stirred for 3 hours at a bath temperature of 140°. It is cooled and worked up in a conventional manner, and 3-[4-(4-m-methoxyphenylpiperazino)butyl]indole-5-carboxamide is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05418237 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-f6566778685e4c7d97edb5d95ee8c66c |
| 출처 메모 | uspto-grants-1995_05 |