Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2,3,4-Tetrahydroquinoline → 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| 반응물 | 4-chloro-5,6-dimethyl-7H-pyrrolo(2,3-d)pyrimidine | HCID 13041144 | — |
| 용매 | Toluene acetone | HCID 20247278 | — |
| 생성물 | 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine | HCID 23282462 | — |
반응 단계
This product is prepared in a manner analogous to that described in Example 1 from 4-chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine and 1,2,3,4-tetrahydroquinoline (4 equivalents, Fluka, Buchs, Switzerland). M.p: 263-264° C.; FAB-MS: (M+H)+ =279 (corresponds to C17H18N4); Rf value (toluene-acetone--(4:6))=0.29.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06140317 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-76ac5485e1334e7499be9b28474d231e |
| 출처 메모 | uspto-grants-2000_10 |