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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 36991생성일: 2026년 10월 25일

4-Methoxybenzyl alcohol → p-Methoxybenzyl acrylate

https://huagongshe.com/reaction/36991

반응식

참여 물질

역할이름HCID투입량
반응물4-Methoxybenzyl alcoholHCID 7738—
반응물(E)-3-[2-n-Butyl-1-[(2-chlorophenyl)methyl]-4-hydroxymethyl-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acidHCID 70041240—
생성물p-Methoxybenzyl acrylateHCID 346146—

반응 단계

(E)-3-[2-n-Butyl-1-[(2-chlorophenyl)methyl]-4-hydroxymethyl-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid, prepared as in Example 19, is esterified with 4-methoxy-benzyl alcohol to give the p-methoxybenzyl propenoate. The 4-hydroxymethyl group in acetone is oxidized using an acidic aqueous solution containing chromic acid (Jones' reagent) and the ester is hydrolyzed using 10% sodium hydroxide to give the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05418250
출처 데이터셋uspto-grants-1995_05
ORD IDord-3862763d9dd040f2bdcc091619a783c9
출처 메모uspto-grants-1995_05