Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-(hydroxymethyl)benzoate → (E)-3-[2-n-Propyl-1-{(4-carboxyphenyl)methyl}-1h-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-(hydroxymethyl)benzoate | HCID 81325 | — |
| 반응물 | 3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid | HCID 10047444 | — |
| 반응물 | Methyl ether hydrochloride | HCID 21585225 | — |
| 생성물 | (E)-3-[2-n-Propyl-1-{(4-carboxyphenyl)methyl}-1h-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic Acid | HCID 36688250 | — |
반응 단계
The title compound was prepared using the procedure of Example 1 replacing valermamidine methyl ether hydrochloride with butyramidine methyl ether hydrochloride and replacing 2-chlorbenzyl alcohol with 4-carbomethoxybenzyl alcohol; mp 250° C. (d).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05418250 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-e5ef573c113d47ec8a15fb229397ea93 |
| 출처 메모 | uspto-grants-1995_05 |