Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boron trifluoride etherate → 2,3,5,6-Tetrafluorophenyl trifluoroacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boron trifluoride etherate | HCID 8000 | — |
| 반응물 | Trifluoroacetic anhydride | HCID 9845 | — |
| 반응물 | 2,3,5,6-Tetrafluorophenol | HCID 69858 | — |
| 생성물 | 2,3,5,6-Tetrafluorophenyl trifluoroacetate | HCID 15334258 | 75% |
반응 단계
Trifluoroacetic anhydride (28 mL, 0.2 mol) was added dropwise with stirring to 27.1 g (0,163 mol) of 2,3,5,6tetrafluorophenol. Boron trifluoride etherate (0.2 mL) was added and the mixture was refluxed overnight. The residual solution was distilled at atmospheric pressure to remove trifluoroacetic anhydride and trifluoroacetic acid. The desired product 18 (32.2 g; 75% yield) was collected at 45° C. (18mm) as a colorless liquid:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05419966 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-0f9b25f93fa74c2990bd28e8b3c03f57 |
| 출처 메모 | uspto-grants-1995_05 |