Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3,5,6-Tetrafluorophenyl 5-(9-Acridinyl)pentanoate → 1-[5-(9-Acridinyl)-1-oxopentyl]-5-hydroxymethyl-(3R-trans)-3-pyrrolidinol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3,5,6-Tetrafluorophenyl 5-(9-Acridinyl)pentanoate | HCID 19934285 | — |
| 반응물 | 1-[5-(9-Acridinyl)-1-oxopentyl]-5-hydroxymethyl-(3R-trans)-3-pyrrolidinol | HCID 22853587 | — |
| 생성물 | Acridine | HCID 9215 | — |
| 생성물 | 1-[5-(9-Acridinyl)-1-oxopentyl]-5-hydroxymethyl-(3R-trans)-3-pyrrolidinol | HCID 22853587 | 92% |
반응 단계
A procedure similar to that described in Example XXIV was used for the preparation of 21. 1.28 g (3.00 mmol) of acridine TFP ester 20 gave 1.04 g (92% yield) of 21 as a pale yellow solid foam:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05419966 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-11b09e838dbb4d5b8db53e3e9d14a692 |
| 출처 메모 | uspto-grants-1995_05 |