L-Alanyl-L-proline → N-[1-ethoxycarbonyl-4,4-ethylenedioxy-4-phenylbutyl]-L-alanyl-L-proline

HRID 370843

반응식

HRID 370843 반응식
[CH2:1]1[CH2:20][O:19][C:3]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)([CH2:4][CH2:5][C:6](=O)[C:7]([O:9][CH2:10][CH3:11])=[O:8])[O:2]1.[NH2:21][C@H:22]([C:24]([N:26]1[CH2:33][CH2:32][CH2:31][C@H:27]1[C:28]([OH:30])=[O:29])=[O:25])[CH3:23]>>[CH2:10]([O:9][C:7]([CH:6]([NH:21][C@H:22]([C:24]([N:26]1[CH2:33][CH2:32][CH2:31][C@H:27]1[C:28]([OH:30])=[O:29])=[O:25])[CH3:23])[CH2:5][CH2:4][C:3]1([O:19][CH2:20][CH2:1][O:2]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:8])[CH3:11]

참가 물질

3

반응물 2

HCID 83525L-Alanyl-L-prolineHCID 20275222Ethyl 5,5-ethylenedioxy-2-oxo-5-phenylpentanoate

생성물 1

HCID 54344795N-[1-ethoxycarbonyl-4,4-ethylenedioxy-4-phenylbutyl]-L-alanyl-L-proline

실험 절차

The process described in Example 17 was repeated using ethyl 5,5-ethylenedioxy-2-oxo-5-phenylpentanoate and L-alanyl-L-proline as starting materials. There was thus obtained as an oil N-[1-ethoxycarbonyl-4,4-ethylenedioxy-4-phenylbutyl]-L-alanyl-L-proline.

출처 및 근거

ORD 기록
ord-33e9c0f9c6874567a2736ca79aae678d
출처 데이터셋
uspto-grants-1985_07
특허 번호
US04528282

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