Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | 2'-Fluoro-2'-deoxyadenosine | HCID 100253 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine hydrochloride | HCID 67740756 | — |
반응 단계
To a solution of 9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)adenine (500 mg. 1.86 mmol) in MeOH (40 ml) and water (10 ml) was added a solution of isopropanol (15 ml) previously saturated with HCl gas. The solution was evaporated under vacuum at room temperature, and triturated with EtOH (25 ml) to afford the title compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05420115 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-6f3bdcf96f5c441380f7fe1672130045 |
| 출처 메모 | uspto-grants-1995_05 |