Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl orthoformate → 7-Chloro-5-methylthio-1,2,4-triazolo[4,3-c]pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl orthoformate | HCID 31214 | — |
| 반응물 | 4-Chloro-6-hydrazinyl-2-(methylsulfanyl)pyrimidine | HCID 1484546 | — |
| 생성물 | 7-Chloro-5-methylthio-1,2,4-triazolo[4,3-c]pyrimidine | HCID 13519858 | — |
반응 단계
A mixture of 7.0 g (0.037 mole) of 4-chloro-6-hydrazino-2-methylthiopyrimidine and 100 ml of triethyl orthoformate was heated at reflux for 48 hours. Cooling provided a precipitate which was isolated by filtration, and then recrystallized from an ethanol-heptane mixture, with treatment with decolorizing charcoal. The product was red crystals of 7-chloro-5-methylthio-1,2,4-triazolo[4,3-c]pyrimidine, m.p. 164°-165° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04532242 |
| 출처 데이터셋 | uspto-grants-1985_07 |
| ORD ID | ord-2132604681b044c0af377e7cdc2929c9 |
| 출처 메모 | uspto-grants-1985_07 |