Methanol → Methyl 4-phenylthiobenzoate

HRID 37149

반응식

HRID 37149 반응식
[C:1]1([C:7]2[CH:15]=[CH:14][C:10]([C:11]([OH:13])=[S:12])=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH3:21]O>>[C:1]1([C:7]2[CH:8]=[CH:9][C:10]([C:11]([O:13][CH3:21])=[S:12])=[CH:14][CH:15]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 178526127HCID 178526127, 화합물

생성물 1

HCID 54459547Methyl 4-phenylthiobenzoate

실험 절차

A mixture of 26.29 g of 4-phenylthiobenzoic acid, 5 ml of concentrates sulfuric acid, and 400 ml of methanol was refluxed for 10 hours while stirring. After reaction, the reaction mixture was concentrated in vacuo, and 400 ml of ethyl acetate was added to the residue, and the mixture was washed with saturated brine (200 ml×3), and dried in anhydrous magnesium sulfate, concentrated in vacuo, and methyl 4phenylthiobenzoate was obtained (27.44 g).

후처리

  1. temperaturewas refluxed for 10 hours
  2. customAfter reaction
  3. concentrationthe reaction mixture was concentrated in vacuo, and 400 ml of ethyl acetate
  4. additionwas added to the residue
  5. washthe mixture was washed with saturated brine (200 ml×3)
  6. dry with materialdried in anhydrous magnesium sulfate
  7. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-533ad2a3f35548f58abae14dec4e6bd0
출처 데이터셋
uspto-grants-1995_05
특허 번호
US05420128

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