2-Chloro-6-methylphenol → 2-Chloro-4-[(3,4-dichlorophenyl)methyl]-6-methylphenol

HRID 371520노트

반응식

HRID 371520 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[OH:9].[Cl:10][C:11]1[CH:12]=[C:13]([CH:16]=[CH:17][C:18]=1[Cl:19])[CH2:14]Cl>O>[Cl:1][C:2]1[CH:7]=[C:6]([CH2:14][C:13]2[CH:16]=[CH:17][C:18]([Cl:19])=[C:11]([Cl:10])[CH:12]=2)[CH:5]=[C:4]([CH3:8])[C:3]=1[OH:9]

참가 물질

4

반응물 2

HCID 68982-Chloro-6-methylphenolHCID 76093,4-Dichlorobenzyl chloride

생성물 1

HCID 202734892-Chloro-4-[(3,4-dichlorophenyl)methyl]-6-methylphenol

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
60 °C

실험 절차

90.4 g (0.63 mol) 2-chloro-6-methylphenol are brought to reaction with 149.4 g (0.765 mol) 3,4-dichlorobenzylchloride and 2.4 g water-free, finely mortared ZnCL2 without solvent. After stirring 5-6 h at 60° C. the reaction mixture is subsequently worked up by washing three times, each with 100 ml water.

후처리

  1. washby washing three times

출처 및 근거

ORD 기록
ord-3b7da3a114114c5ab5eb9a01eb9ae00a
출처 데이터셋
uspto-grants-1985_07
특허 번호
US04532367

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