Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 6-acetyl-1,4-benzodioxin-2-carboxylate → Ethyl 6-ethyl-2,3-dihydro-1,4-benzodioxin-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 6-acetyl-1,4-benzodioxin-2-carboxylate | HCID 11806994 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | Ethyl 6-ethyl-2,3-dihydro-1,4-benzodioxin-2-carboxylate | HCID 15210220 | 70% |
반응 단계
Hydrogenate a solution of 3 g of ethyl 6-acetyl-1,4-benzodioxin-2-carboxylate in 15 cm3 of acetic acid under hydrogen pressure (50 psi) in the presence of 0.750 g of 5% palladium on carbon. The crude product obtained by concentrating to dryness is purified by chromatography on a silica column (eluant: petroleum ether/diethyl ether, 70:30). Ethyl 6-ethyl-2,3-dihydro-1,4-benzodioxin-2-carboxylate is thereby obtained in a yield of 70%. ##STR29##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05420132 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-a66b2c3fc8ae43888555b4bd5fc2fbdc |
| 출처 메모 | uspto-grants-1995_05 |