Diethylcarbamoyl chloride → HCID 20354992, 화합물
반응식
[CH2:1]([S:3][C:4]1[N:8]=[CH:7][NH:6][N:5]=1)[CH3:2].[CH2:9]([N:11]([CH2:15][CH3:16])[C:12](Cl)=[O:13])[CH3:10].O1CCCC1.C(N(CC)CC)C>CCOCC>[CH2:9]([N:11]([CH2:15][CH3:16])[C:12]([N:6]1[CH:7]=[N:8][C:4]([S:3][CH2:1][CH3:2])=[N:5]1)=[O:13])[CH3:10]참가 물질
6
실험 절차
A mixture of 6.45 g. 3-ethylthio-1,2,4-triazole, 7.5 g. diethylcarbamoyl chloride, 40 ml. dry tetrahydrofuran and 7.75 ml. dry triethylamine was refluxed under anhydrous conditions for 22 hours. The reaction mixture was worked up as described in Example 1, using ether in place of methylene dichloride, to give a residual oil. This oil was distilled under reduced pressure to give 1-diethylcarbamoyl-3-ethylthio-1,2,4-triazole, b.p. 110° - 111° C./0.2 mm. (93.6% 1-isomer by GLC assay). Elemental analysis satisfactory.
후처리
- additionA mixture of 6.45 g
- customto give a residual oil
- distillationThis oil was distilled under reduced pressure
출처 및 근거
- ORD 기록
- ord-769b4531b7d6442eb8515ccf638d2f61
- 출처 데이터셋
- uspto-grants-1978_05
- 특허 번호
- US04087269
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