Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tert-Butylamine → [(t-Butylcarbamoyl)methyl]phosphonic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tert-Butylamine | HCID 6385 | — |
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | 2-(Dimethoxyphosphoryl)acetic acid | HCID 189964 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | [(t-Butylcarbamoyl)methyl]phosphonic acid | HCID 22748653 | — |
반응 단계
Tertiary butyl amine (0.045 mole) and dimethyl (carboxymethyl)phosphonate (0.04 mole) were dissolved in 100 ml. of methylene chloride. As the solution was stirred, dicyclohexylcarbodiimide was added portionwise. The solution was stirred overnight and the mixture filtered. The filtrate was concentrated to a solid. It was recrystallized from an appropriate solvent such as methanol. m.p. 163°-5° C., yield, 61%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04087522 |
| 출처 데이터셋 | uspto-grants-1978_05 |
| ORD ID | ord-fdc5e424f1ab4d7eb193b14a80ef3588 |
| 출처 메모 | uspto-grants-1978_05 |