반응식
[OH:1][CH2:2][C@@:3]12[C@@H:20]3[C@H:11]([C@H:12]4[C@@:16]([CH2:18][CH2:19]3)([CH3:17])[C:15](=[O:21])[CH2:14][CH2:13]4)[CH2:10][CH2:9][C:8]1=[CH:7][C:6](=[O:22])[CH2:5][C@H:4]2[CH3:23].[OH:24][CH2:25][C@@:26]12[C@@H:43]3[C@H:34]([C@H:35]4[C@@:39]([CH2:41][CH2:42]3)([CH3:40])[C:38](=[O:44])[CH2:37][CH2:36]4)[CH2:33][C@H:32]([CH3:45])[C:31]1=[CH:30][C:29](=[O:46])[CH2:28][CH2:27]2.C[O-].[C:49]1([Si:55]([C:84]2[CH:89]=[CH:88][CH:87]=[CH:86][CH:85]=2)([C:78]2[CH:83]=[CH:82][CH:81]=[CH:80][CH:79]=2)OC[C@@]23[C@@H]4[C@H]([C@H]5[C@@](CC4)(C)C(=O)CC5)CCC2=CC(=O)CC3)[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=1>>[CH3:23][C@H:4]1[C@@:3]2([CH2:2][O:1][Si:55]([C:78]3[CH:79]=[CH:80][CH:81]=[CH:82][CH:83]=3)([C:84]3[CH:89]=[CH:88][CH:87]=[CH:86][CH:85]=3)[C:49]3[CH:50]=[CH:51][CH:52]=[CH:53][CH:54]=3)[C:8]([CH2:9][CH2:10][C@@H:11]3[C@@H:20]2[CH2:19][CH2:18][C@@:16]2([CH3:17])[C@H:12]3[CH2:13][CH2:14][C:15]2=[O:21])=[CH:7][C:6](=[O:22])[CH2:5]1.[CH3:45][C@@H:32]1[C:31]2[C@:26]([CH2:25][O:24][Si:55]([C:78]3[CH:79]=[CH:80][CH:81]=[CH:82][CH:83]=3)([C:84]3[CH:89]=[CH:88][CH:87]=[CH:86][CH:85]=3)[C:49]3[CH:50]=[CH:51][CH:52]=[CH:53][CH:54]=3)([CH2:27][CH2:28][C:29](=[O:46])[CH:30]=2)[C@@H:43]2[C@H:34]([C@H:35]3[C@@:39]([CH2:41][CH2:42]2)([CH3:40])[C:38](=[O:44])[CH2:37][CH2:36]3)[CH2:33]1참가 물질
5
반응물 3
생성물 2
실험 절차
Following essentially the same procedure but substituting 19-hydroxy-1β-methyl-4-androstene-3,17-dione and 19-hydroxy-6α-methyl-4-androstene-3,17-dione for the 19-hydroxy-4-androstene-3,17-dione above results in the preparation of 1β-methyl-19-triphenylsiloxy-4-androstene-3,17-dione and 6α-methyl-19-triphenylsiloxy-4-androstene-3,17-dione.
출처 및 근거
- ORD 기록
- ord-b4c906bcf4c147b3900b530dee47499a
- 출처 데이터셋
- uspto-grants-1978_05
- 특허 번호
- US04087524
연결된 노트
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