Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 19-Methoxyandrost-4-ene-3,17-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 19-Hydroxyandrostenedione | HCID 252379 | — |
| 반응물 | Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) | HCID 2735153 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 19-Methoxyandrost-4-ene-3,17-dione | HCID 54153042 | — |
반응 단계
19-Hydroxyandrost-4-ene-3,17-dione is dissolved in methylenechloride and trimethyloxonium fluoroborate added. After stirring at room temperature for a period of two hours, water is added to the reaction mixture, the organic layer is separated, dried over magnesium sulfate and the solvent removed under vacuum. The residue is crystallized from an acetone-hexane solution to yield the desired 19-methoxyandrost-4-ene-3,17-dione.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04087524 |
| 출처 데이터셋 | uspto-grants-1978_05 |
| ORD ID | ord-375ad16dbc2f48c98abcf840ec02c66b |
| 출처 메모 | uspto-grants-1978_05 |