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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 371890생성일: 2026년 10월 26일

Water → 2-[p-(2,4-Dichlorobenzyl)-phenoxi]-propionic acid amide

https://huagongshe.com/reaction/371890

반응식

참여 물질

역할이름HCID투입량
반응물WaterHCID 962—
반응물Potassium CarbonateHCID 11430—
반응물2-BromopropanamideHCID 101118—
반응물4-(2,4-Dichlorobenzyl)-phenolHCID 13938709—
용매DimethylformamideHCID 6228—
생성물2-[p-(2,4-Dichlorobenzyl)-phenoxi]-propionic acid amideHCID 70622740—

반응 단계

A solution of 25.3 g of 4-(2,4-dichlorobenzyl)-phenol and 15.2 g of α-bromopropionic acid amide in 100 ml of dimethyl formamide was stirred for 2 hours at 100° C together with 16 g of potassium carbonate. After cooling, the reaction mixture was poured into 1 liter of water. A viscous oil precipitated which was absorbed in methylene chloride and washed with water. After drying over sodium sulfate, the solvent was distilled off under reduced pressure. The remaining colorless crystals were recrystallized from methanol. Yield: 25.8 g; melting point 148° - 149° C. ##STR5##

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04088474
출처 데이터셋uspto-grants-1978_05
ORD IDord-5991b704c0034b9283fb1896623af89d
출처 메모uspto-grants-1978_05