Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-[p-(2,4-Dichlorobenzyl)-phenoxi]-propionic acid amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Bromopropanamide | HCID 101118 | — |
| 반응물 | 4-(2,4-Dichlorobenzyl)-phenol | HCID 13938709 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-[p-(2,4-Dichlorobenzyl)-phenoxi]-propionic acid amide | HCID 70622740 | — |
반응 단계
A solution of 25.3 g of 4-(2,4-dichlorobenzyl)-phenol and 15.2 g of α-bromopropionic acid amide in 100 ml of dimethyl formamide was stirred for 2 hours at 100° C together with 16 g of potassium carbonate. After cooling, the reaction mixture was poured into 1 liter of water. A viscous oil precipitated which was absorbed in methylene chloride and washed with water. After drying over sodium sulfate, the solvent was distilled off under reduced pressure. The remaining colorless crystals were recrystallized from methanol. Yield: 25.8 g; melting point 148° - 149° C. ##STR5##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04088474 |
| 출처 데이터셋 | uspto-grants-1978_05 |
| ORD ID | ord-5991b704c0034b9283fb1896623af89d |
| 출처 메모 | uspto-grants-1978_05 |