Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluoroaniline → N-(4-fluorophenyl)-2-[[2-[(4-fluorophenyl)carbamoyl]phenyl]disulfanyl]benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluoroaniline | HCID 9731 | — |
| 반응물 | 2,2'-Dithiodibenzoyl chloride | HCID 88164 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(4-fluorophenyl)-2-[[2-[(4-fluorophenyl)carbamoyl]phenyl]disulfanyl]benzamide | HCID 465337 | 9.7% |
반응 단계
This compound was prepared according to the general method of Example 77 using 2,2'-dithiobisbenzoyl chloride (1.00 g, 2.92 mmol) in 20 mL of dichloromethane and 4-fluoroaniline (0.657 g, 5.91 mmol) in 5 mL of pyridine. The crude product was triturated with hot ethanol-ethyl acetate mixture, filtered, and recrystallized from ethanol-DMF to yield 0.14 g of the title compound, mp 242°-244° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05734081 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-1e404142def44ea88cbeeff7e6caace1 |
| 출처 메모 | uspto-grants-1998_03 |