3-(Trifluoromethyl)aniline → 2,2'-Dithiobis(N-(3-(trifluoromethyl)phenyl)benzamide)

HRID 3720

반응식

HRID 3720 반응식
[C:1](Cl)(=[O:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][S:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[C:12](Cl)=[O:13].[NH2:21][C:22]1[CH:23]=[C:24]([C:28]([F:31])([F:30])[F:29])[CH:25]=[CH:26][CH:27]=1>ClCCl.N1C=CC=CC=1>[F:31][C:28]([F:29])([F:30])[C:24]1[CH:23]=[C:22]([NH:21][C:1](=[O:19])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[S:8][S:9][C:10]2[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=2[C:12]([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]([F:29])([F:30])[F:31])[CH:23]=2)=[O:13])[CH:27]=[CH:26][CH:25]=1

참가 물질

5

반응물 2

HCID 73753-(Trifluoromethyl)anilineHCID 881642,2'-Dithiodibenzoyl chloride

생성물 1

HCID 4574692,2'-Dithiobis(N-(3-(trifluoromethyl)phenyl)benzamide)수율 15.1%

시약·촉매·용매 2

HCID 1049Pyridine용매HCID 6344Dichloromethane용매

실험 절차

This compound was prepared according to the general method of Example 77 using 2,2'-dithiobisbenzoyl chloride (2.00 g, 5.83 mmol) in 50 mL of dichloromethane and 3-aminobenzotrifluoride (1.87 g, 11.6 mmol) in 15 mL of pyridine. The crude product was recrystallized from ethanol, then ethyl ether to yield 0.519 g of the title compound, mp 167°-168° C.

후처리

  1. customThis compound was prepared
  2. customThe crude product was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-2ee1555109fc4f4f898ac529b39d3c5b
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05734081

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