Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 2-(1-Methyl-4-imidazolyl)ethylguanidine sulphate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | S-methyl isothiourea hemisulfate | HCID 6604939 | — |
| 반응물 | 1-Methylhistamine dihydrochloride | HCID 11957601 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-(1-Methyl-4-imidazolyl)ethylguanidine sulphate | HCID 178481270 | — |
반응 단계
An aqueous solution of S-methylthiouronium sulphate (2.1 g) is added to a solution prepared from 1-methyl-4-(2-aminoethyl)imidazole dihydrochloride (3.0 g) and sodium hydroxide (1.21 g) in water. The resultant solution is heated under reflux for 17 hours. The product, isolated in a manner similar to that described in Example 1 is recrystallized from aqueous ethanol yielding pure 2-(1-methyl-4-imidazolyl)ethylguanidine sulphate, m.p. 280°-282° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04088769 |
| 출처 데이터셋 | uspto-grants-1978_05 |
| ORD ID | ord-ab8156ea395f48b1abfaeb368f94d37e |
| 출처 메모 | uspto-grants-1978_05 |