Ethylamine → Trans 3-chloro-N-ethylcinnamamide

HRID 372483노트

반응식

HRID 372483 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)/[CH:5]=[CH:6]/[C:7](Cl)=[O:8].[CH2:13]([NH2:15])[CH3:14]>C1C=CC=CC=1.CCOCC>[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)/[CH:5]=[CH:6]/[C:7]([NH:15][CH2:13][CH3:14])=[O:8]

참가 물질

5

반응물 2

HCID 6341EthylamineHCID 11008963(2E)-3-(3-chlorophenyl)prop-2-enoyl chloride

생성물 1

HCID 6015846Trans 3-chloro-N-ethylcinnamamide

시약·촉매·용매 2

HCID 241Benzene용매HCID 3283Diethyl Ether용매

실험 절차

Trans 3-chlorocinnamoyl chloride (4.4 g) in dry benzene (75 ml) was allowed to react with an excess of ethylamine in dry ether (75 ml) according to the procedure of Example 2. Trans 3-chloro-N-ethylcinnamamide, m.p. 87°-88° C, was obtained which had NMR, IR, and elemental analysis consistent with this structure.

출처 및 근거

ORD 기록
ord-1befbc1118f24a81a03580a7702c7203
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04091112

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