Nitric Acid → 3-(3-Nitrobenzoyl)acrylic acid

HRID 372576

반응식

HRID 372576 반응식
[C:1]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:14]([O-])([OH:16])=[O:15]>>[N+:14]([C:4]1[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=1)[C:1]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])=[O:8])([O-:16])=[O:15]

참가 물질

3

반응물 2

HCID 944Nitric AcidHCID 94714Beta-benzoylacrylic acid

생성물 1

HCID 2357513-(3-Nitrobenzoyl)acrylic acid

실험 절차

22 g of finely powdered 3-benzoylacrylic acid was added in 1-gram portions to 11° g of stirred fuming (90%) nitric acid at -5° over a 30-minute period, the mixture being allowed to heat to 0°. Then the temperature of the mixture was allowed to rise to 2° and held until a clear solution was obtained. The mixture then was poured on ice, and the solid which formed was filtered, washed with water, dried (MgS04) and recrystallized from ethanol to give 3-(3-nitrobenzoyl)acrylic acid (8A), m.p.: 199°-201°.

후처리

  1. temperatureto heat to 0°
  2. customto rise to 2°
  3. customwas obtained
  4. additionThe mixture then was poured on ice
  5. customthe solid which formed
  6. filtrationwas filtered
  7. washwashed with water
  8. customdried (MgS04)
  9. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-10352e81e93d4dd79a04958ae164118c
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04091221

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