HCID 22803567, 화합물 → HCID 22803568, 화합물

HRID 372781노트

반응식

HRID 372781 반응식
ClC1C=C(Cl)C(Cl)=CC=1O[C:11](=[O:27])[C@H:12]([CH2:21][C:22]1[S:23][CH:24]=[CH:25][CH:26]=1)[NH:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15].[CH2:28]([O:35][C:36](=[O:64])[C@H:37]([CH2:60][CH2:61][S:62][CH3:63])[NH:38]C(=O)[C@H](CC1C2C(=CC=CC=2)NC=1)NC(OC(C)(C)C)=O)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[CH2:28]([O:35][C:36](=[O:64])[C@H:37]([CH2:60][CH2:61][S:62][CH3:63])[NH:38][C:11](=[O:27])[C@H:12]([CH2:21][C:22]1[S:23][CH:24]=[CH:25][CH:26]=1)[NH:13][C:14]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:15])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1

참가 물질

3

반응물 2

HCID 22803567HCID 22803567, 화합물HCID 53790063HCID 53790063, 화합물

생성물 1

HCID 22803568HCID 22803568, 화합물

실험 절차

When an equivalent quantity of N-t-butoxycarbonyl-β-(2-thienyl)-L-alanine 2,4,5-trichlorophenyl ester is substituted for the N-t-butoxycarbonyl-L-tryptophan 2,4,5-trichlorophenyl ester of Example 5 and the procedure detailed therein substantially repeated, there is obtained N-t-butoxycarbonyl-β-(2-thienyl)-L-alanyl-L-methionine benzyl ester.

출처 및 근거

ORD 기록
ord-ba2d4fca2e1e44efa7b69f240bd0bcdb
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04092304

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