Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 2-(1-Naphthyl)-2-(methoxycarbonyl)acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 1-Naphthaleneacetonitrile | HCID 8596 | — |
| 반응물 | Dimethyl Carbonate | HCID 12021 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 생성물 | 2-(1-Naphthyl)-2-(methoxycarbonyl)acetonitrile | HCID 10846815 | — |
반응 단계
0.1 mol of 2-(1-naphthyl)acetonitrile is dissolved in 120 cm3 of dimethyl carbonate, and the solution is heated to reflux. 0.1 mol of sodium is then added in small portions over 30 min, during which time the methanol evaporates off. The reaction medium is kept refluxing for 1 hour, and the excess dimethyl carbonate is then evaporated off to dryness. The residue is taken up with 100 cm3 of an 18% solution of acetic acid in water.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05420158 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-87392b3e925043f0acdd97a4f40532ee |
| 출처 메모 | uspto-grants-1995_05 |