Gluconic Acid → HCID 67620484, 화합물

HRID 373089노트

반응식

HRID 373089 반응식
[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:10]=[C:11]([NH:15][C:16]3[N:21]=[C:20]([C:22]4[S:23][CH:24]=[CH:25][CH:26]=4)[CH:19]=[CH:18][N:17]=3)[CH:12]=[CH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[O:27]=[C:28]([OH:39])[C@@H:29]([C@H:31]([C@@H:33]([C@@H:35]([CH2:37][OH:38])[OH:36])[OH:34])[OH:32])[OH:30]>C(O)C>[O:27]=[C:28]([OH:39])[C@@H:29]([C@H:31]([C@@H:33]([C@@H:35]([CH2:37][OH:38])[OH:36])[OH:34])[OH:32])[OH:30].[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:10]=[C:11]([NH:15][C:16]3[N:21]=[C:20]([C:22]4[S:23][CH:24]=[CH:25][CH:26]=4)[CH:19]=[CH:18][N:17]=3)[CH:12]=[CH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

참가 물질

4

반응물 2

HCID 10690Gluconic AcidHCID 9820417N-[3-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine

생성물 1

HCID 67620484HCID 67620484, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

To a solution of 1.0 g of N-[3-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine in 10 ml of hot ethyl alcohol is added 5 ml of ethyl alcohol containing 0.54 g of gluconic acid. Crystals begin to form and the reaction mixture is cooled. The solid is collected by filtration, washed with ethyl alcohol and dried to afford the desired product.

후처리

  1. customto form
  2. temperaturethe reaction mixture is cooled
  3. filtrationThe solid is collected by filtration
  4. washwashed with ethyl alcohol
  5. customdried

출처 및 근거

ORD 기록
ord-31fdd5f09207422f868743c4fba54aec
출처 데이터셋
uspto-grants-1992_11
특허 번호
US05162328

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