1,3-Dimethyl-5-ethoxycarbonylbarbituric acid → HCID 19811558, 화합물

HRID 373105노트

반응식

HRID 373105 반응식
[F:1][C:2]([F:23])([O:9][CH:10]([F:22])[C:11]([F:21])([F:20])[O:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][CH:14]=1)[C:3]([F:8])([F:7])[CH:4]([F:6])[F:5].[CH3:24][N:25]1[C:32](=[O:33])[CH:31]([C:34](OCC)=[O:35])[C:29](=[O:30])[N:28]([CH3:39])[C:26]1=[O:27]>C1(C)C=CC=CC=1>[CH3:39][N:28]1[C:29](=[O:30])[CH:31]([C:34](=[O:35])[NH:17][C:16]2[CH:18]=[CH:19][C:13]([O:12][C:11]([F:21])([F:20])[CH:10]([O:9][C:2]([F:23])([F:1])[C:3]([F:7])([F:8])[CH:4]([F:5])[F:6])[F:22])=[CH:14][CH:15]=2)[C:32](=[O:33])[N:25]([CH3:24])[C:26]1=[O:27]

참가 물질

4

반응물 2

HCID 5937141,3-Dimethyl-5-ethoxycarbonylbarbituric acidHCID 14819451HCID 14819451, 화합물

생성물 1

HCID 19811558HCID 19811558, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

14.50 g (40.6 mmol) of 4-(2-(1,1,2,2,3,3-hexafluoropropoxy)-1,1,2-trifluoroethoxy)-aniline were added to 9.26 g (40.6 mmol) of 1,3-dimethyl-5-ethoxycarbonylbarbituric acid in 100 ml of toluene, the mixture was stired under reflux for 2.5 hours and concentrated and the residue was recrystallized from methanol.

후처리

  1. temperatureunder reflux for 2.5 hours
  2. concentrationconcentrated
  3. customthe residue was recrystallized from methanol

출처 및 근거

ORD 기록
ord-df7e9aa50fd54996b8f60d7cfc04b264
출처 데이터셋
uspto-grants-1992_11
특허 번호
US05162327

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