Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chlorothiophene → Methanone, (5-chloro-2-thienyl)phenyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chlorothiophene | HCID 7299 | — |
| 반응물 | 4-tert-Butylphenol | HCID 7393 | — |
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 생성물 | Methanone, (5-chloro-2-thienyl)phenyl- | HCID 901505 | — |
| 생성물 | 2-Benzoyl-5-(4-t-butyl-phenoxy)thiophene | HCID 19935313 | — |
반응 단계
2-benzoyl-5-chlorothiophene was synthesized via Friedel-Crafts acylation of benzoyl chloride with 2-chlorothiophene. This was reacted under standard conditions with 4-t-butyl phenol to produce 2-benzoyl-5-(4-t-butyl-phenoxy)thiophene. It was discovered by thin layer chromatography that the displacement of the acyl chlorine proceeds completely with no side reactions. Complete nucleophilic displacement demonstrates that this reaction meets the requirements necessary for high polymer formation via a step growth reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05420224 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-fefca5a18f9547ababd952357d410f7f |
| 출처 메모 | uspto-grants-1995_05 |