Cytidine → 4-amino-1-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

HRID 37348

반응식

HRID 37348 반응식
[C@@H:1]1([N:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[N:12][C:11]2=[O:17])[O:7][C@H:6]([CH2:8][OH:9])[C@@H:4]([OH:5])[C@H:2]1[OH:3].[OH-].[K+]>CO>[C@H:1]1([N:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[N:12][C:11]2=[O:17])[O:7][C@H:6]([CH2:8][OH:9])[C@@H:4]([OH:5])[C@H:2]1[OH:3]

참가 물질

4

반응물 2

HCID 6175CytidineHCID 14797Potassium Hydroxide

생성물 1

HCID 12659014-amino-1-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

The process of claim 27 wherein 1-(β-D-ribofuranosyl)-4-aminopyrimidin-2-one is contacted with potassium hydroxide in methanol to form 1-(α-D-ribofuranosyl)-4-aminopyrimidin-2-one

출처 및 근거

ORD 기록
ord-12b6769bb04b422a8e38d1043b6f9c35
출처 데이터셋
uspto-grants-1995_05
특허 번호
US05420266

연결된 노트

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