참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylhydantoin | HCID 6491 | — |
| 반응물 | Diphenyl Ether | HCID 7583 | — |
| 반응물 | 5-Chloro-2-nitrobenzotrifluoride | HCID 67052 | — |
| 생성물 | Nilutamide | HCID 4493 | — |
반응 단계
The following were introduced into 288 ml of phenyl oxide: 96.10 grams of 5,5-dimethyl-hydantoin, 170.86 grams of 2-nitro-5-chloro trifluoromethylbenzene and 89.40 grams of cupric oxide. The mixture was heated to 190° C. for about 23 hours, then cooled to 20° C. and filtered. The residue was characterized in the phenyl oxide filtrate by thin layer chromatography.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05166358 |
|---|
| 출처 데이터셋 | uspto-grants-1992_11 |
|---|
| ORD ID | ord-250000bbc78844a9a114c6ed9b1ccd4b |
|---|
| 출처 메모 | uspto-grants-1992_11 |
|---|
