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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 374136생성일: 2026년 10월 25일

4-Methylbenzylamine → N-cyano-N'-(4-methylbenzyl)-2-pyridinecarboximidamide

https://huagongshe.com/reaction/374136

반응식

참여 물질

역할이름HCID투입량
반응물4-MethylbenzylamineHCID 66035—
반응물2-Pyridinecarboximidic acid, N-cyano-, methyl esterHCID 10012189—
용매MethanolHCID 887—
생성물N-cyano-N'-(4-methylbenzyl)-2-pyridinecarboximidamideHCID 1973455391%

반응 단계

Methyl N-cyano-2-pyridinecarboximidate (0.30 g, 1.9 mmol) was dissolved in methanol (10 ml), p-methylbenzylamine (0.25 g, 2.1 mmol) was added, and the resulting mixture was stirred at room temperature for 2 hours. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from diethyl ether to give the title compound (0.41 g, 1.6 mmol, yield: 91%) as colorless crystals.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05166347
출처 데이터셋uspto-grants-1992_11
ORD IDord-cf159c4637df45b0a4c5b542cdfa9f26
출처 메모uspto-grants-1992_11