Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Mercaptobenzoic Acid → 2-[2-(4-Sulfamoylphenylcarbamoyl)phenyldisulfanyl]benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Mercaptobenzoic Acid | HCID 5443 | — |
| 반응물 | 4-(3-Oxo-1,2-benzothiazol-2-yl)benzenesulfonamide | HCID 462938 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-[2-(4-Sulfamoylphenylcarbamoyl)phenyldisulfanyl]benzoic acid | HCID 10766395 | 95.5% |
반응 단계
This compound was prepared according to the method of Example 132 using a suspension of 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzene sulfonamide in a mixture of 15 mL of methanol and 15 mL of tetrahydrofuran, and 0.23 g (1.5 mmol) of thiosalicylic acid. The product was washed with ether and dried in vacuo to give 0.66 g of the title compound, mp 276°-278° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05734081 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-40ccfc0f214f4effb36ca78515638c20 |
| 출처 메모 | uspto-grants-1998_03 |