Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl ethylphosphonate → Ethyl 3-(ethoxycarbonyl)-3-(ethoxy-ethylphosphinyl)propionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl ethylphosphonate | HCID 6534 | — |
| 반응물 | Diethyl fumarate | HCID 638144 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Ethyl 3-(ethoxycarbonyl)-3-(ethoxy-ethylphosphinyl)propionate | HCID 15052087 | 90.9% |
반응 단계
172 g of diethyl fumarate are slowly added at 65°-70° C. under nitrogen to a mixture of 140 g of diethyl ethanephosphonate in 46 g of ethanol. After a further 3 hours the solvent (excess ethanol and diethyl ether) is removed by vacuum distillation; the crude product is obtained in a yield of 285 g with a 95.7% purity, which corresponds to a theoretical yield of 90.9%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05166385 |
| 출처 데이터셋 | uspto-grants-1992_11 |
| ORD ID | ord-d0758f6a49c84695af6163c5c5e758e4 |
| 출처 메모 | uspto-grants-1992_11 |