Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenol → Methyl 3-(phenyl-methoxyphosphinyl)-2-chloropropionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenol | HCID 996 | — |
| 반응물 | Methyl 2-chloroacrylate | HCID 6659 | — |
| 반응물 | Phosphonic acid, phenyl-, dimethyl ester | HCID 75234 | — |
| 생성물 | Methyl 3-(phenyl-methoxyphosphinyl)-2-chloropropionate | HCID 15052091 | 90.1% |
반응 단계
138 g of dimethyl phenylphosphonate are slowly added at 20° C. under nitrogen to a solution of 120.5 g of methyl 2-chloroacrylate and 94 g of phenol. After a reaction time of 3 hours at 70° C. phenetole is removed by vacuum distillation. The residue represents 267 g of crude product with a 93.0% purity, which corresponds to a theoretical yield of 90.1%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05166385 |
| 출처 데이터셋 | uspto-grants-1992_11 |
| ORD ID | ord-3307f53977b44fc8a76ecf241fbf580d |
| 출처 메모 | uspto-grants-1992_11 |