Hexane → 4-(3-t-Butylureidomethyl)-1-aminomethylbenzene
반응식
[C:1]1([CH2:9][NH2:10])[CH:6]=[CH:5][C:4]([CH2:7][NH2:8])=[CH:3][CH:2]=1.CCCCCC.[C:17]([N:21]=[C:22]=[O:23])([CH3:20])([CH3:19])[CH3:18]>C(Cl)Cl>[C:17]([NH:21][C:22](=[O:23])[NH:8][CH2:7][C:4]1[CH:5]=[CH:6][C:1]([CH2:9][NH2:10])=[CH:2][CH:3]=1)([CH3:20])([CH3:19])[CH3:18]참가 물질
5
실험 절차
To a solution of 2.7 g p-xylylenediamine in 100 ml methylene dichloride, was added slowly with stirring 10 ml of a n-hexan solution containing 990 mg t-butyl isocyanate under ice cooling. Stirring was continued at room temperature for two hours, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography, giving 1 g of 4-(3-t-butylureidomethyl)-1-aminomethylbenzene.
후처리
- distillationthe solvent was distilled off under reduced pressure
- customthe residue was purified by silica gel column chromatography
출처 및 근거
- ORD 기록
- ord-284a5578654e45f49e0ae5dd23284035
- 출처 데이터셋
- uspto-grants-1992_11
- 특허 번호
- US05166429
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