Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydroxyphenylacetic acid → 2,6-Dimethylcyclohexyl 4-hydroxyphenylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydroxyphenylacetic acid | HCID 127 | — |
| 반응물 | Benzene | HCID 241 | — |
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | 2,6-Dimethylcyclohexanol | HCID 21428 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2,6-Dimethylcyclohexyl 4-hydroxyphenylacetate | HCID 54109104 | 51% |
반응 단계
A mixture of 2,6-dimethylcyclohexyl alcohol (11.4 g), 4-hydroxyphenylacetic acid (9.12 g), p-toluenesulfonic acid (1 g) and benzene (300 mL) was refluxed with continuous water separation for 20 hours. The mixture was filtered and the filtrate was washed with a 10% Na2CO3 solution, then with water. Drying over MgSO4 and evaporation in vacuo afforded 8.02 g of 2,6-dimethylcyclohexyl 4-hydroxyphenylacetate. That product has the structural formula: ##STR26##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05482961 |
| 출처 데이터셋 | uspto-grants-1996_01 |
| ORD ID | ord-2c76f13321f34205bf38e49ccfc694fa |
| 출처 메모 | uspto-grants-1996_01 |