Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-2-nitro-1,3-propanediol → 5-Methyl-5-nitro-1,3-dioxan-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-2-nitro-1,3-propanediol | HCID 6480 | — |
| 반응물 | Ethylene carbonate | HCID 7303 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 5-Methyl-5-nitro-1,3-dioxan-2-one | HCID 18996054 | — |
반응 단계
A solution of 2-methyl-2-nitro-1,3-propanediol and ethylene carbonate is heated overnight. The reaction mixture is diluted with ethyl acetate and the solution is washed with water. The organic phase is dried and concentrated to obtain 5-methyl-5-nitro-1,3-dioxan-2-one. This is dissolved in methanol and hydrogenated under pressure to give the 5amino compound which is acylated with dodecanoyl chloride to give the product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05482965 |
| 출처 데이터셋 | uspto-grants-1996_01 |
| ORD ID | ord-95f89e8157fe4d36923e6412f8b53d05 |
| 출처 메모 | uspto-grants-1996_01 |