Water → 5-Bromo-6-hydroxy-2-naphthaldehyde

HRID 374869

반응식

HRID 374869 반응식
[Br:1]Br.[OH:3][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[CH:10]=[C:9]([CH:14]=[O:15])[CH:8]=[CH:7]2.O>C(O)(=O)C>[Br:1][C:5]1[C:4]([OH:3])=[CH:13][CH:12]=[C:11]2[C:6]=1[CH:7]=[CH:8][C:9]([CH:14]=[O:15])=[CH:10]2

참가 물질

5

반응물 3

HCID 962WaterHCID 24408BromineHCID 27641106-Hydroxy-2-naphthaldehyde

생성물 1

HCID 189963195-Bromo-6-hydroxy-2-naphthaldehyde수율 94%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

Step b) Bromine (7.45 mL, 145.3 mmol) was added dropwise to a cold (0° C.) solution of 6-hydroxy-2-naphthaldehyde (25.0 g, 145.3 mmol) in acetic acid (300 mL). After stirring for 30 minutes the mixture was poured into water (21), and the precipitated solid filtered and dried to yield a brown solid (34.5 g, 94% yield, m.p. 189-190).

후처리

  1. filtrationthe precipitated solid filtered
  2. customdried
  3. customto yield a brown solid (34.5 g, 94% yield, m.p. 189-190)

출처 및 근거

ORD 기록
ord-e3c8938ecf0449b9b05442428f6fd33f
출처 데이터셋
uspto-grants-1996_01
특허 번호
US05482968

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